A model of a single two-staged global supply chain is set up.The necessary production scale,costs,profits and other indicators are calculated for the global supply chain enterprises to migrate to port cluster based on NetLogo simulation platform.Repeated experiments indicates that the port as an important node in the global supply chain will attract supply chain enterprises to agglomerate to port cluster.And the main factors are analyzed by further tests under the premise that the other variables remain unchanged.Since enterprises in a global supply chain are dynamic,the economic issues for foreign suppliers to enter the global supply chain in the port cluster are discussed by game theory based on Cournot and Stackelberg model.