Abstract:To solve multi distribution center location problem(MDLP) directly, MDLP was mapped into the process of expanded K TSP and improved ants colony algorithm was designed. The setting mode of tabu for classic ants colony algorithm was changed, specifically, when algorithm run, a sharing tabu for ants colony was constructed and all the distribution points the ants had traversed were put into it, any ants could only choose the customer point unrecorded in it, thereby this intensified exchange of information among ants and promoted their division and cooperation, so that the ants visited all the distribution sites exhaustively without repetition, and finally found the optimal solution. In order to improve the algorithm’s performance, price guided function was added to ants’ selection rule, and 2 opt strategy was used to optimize the feasible solution, and optimized pheromone update policy was designed. The simulation example and the algorithm comparison show that the model and the algorithm may express and solve MDLP effectively.