Abstract:After Experience of dry-wet cycle,Its mechanical properties will be irreversible changes. The mechanical properties influenced on moisture content changes cyclicity of cohesive subgrade soil was studied by indoor test. And the extent of the resilience modulus attenuation of subgrade result in frequently dry-wet cycle was analyzed. Use the method of a series of humidity cycle as “water seepage under the permeable stone –standing-oven dehydration……” to imitate the scene of the subgrade soil moisture content fluctuation process. The resilience of subgrade soil was tested by the system of UTM. The results show that, moisture content changes cyclicity have influence in resilience modulus of cohesive subgrade soil. The resilience modulus decrease following the increase of cycle times. In the same stress state, The higher the equilibrium moisture content, The more sensitive the resilience modulus changes.