二聚酸修饰羟基磷灰石的研究

Study on Hydroxyapatite Modified by Dimer Acid

摘要:

以C36二聚酸与多孔羟基磷灰石为原料，在不同溶剂和反应工艺条件下制备二聚酸修饰的羟基磷灰石.采用傅立叶红外光谱仪、激光粒度仪、比表面积孔径测试仪和扫描电镜等方法对其结构进行了表征，用热失重分析法估算了反应程度.结果表明：当C36二聚酸与多孔羟基磷灰石质量比为1∶1，在乙醇溶剂中105~110 ℃下反应3.5~4.0 h，反应程度可达到36%，并可制得二聚酸修饰的多孔羟基磷灰石，二聚酸存在于羟基磷灰石的表面和孔结构中，会导致孔隙率减少.羟基磷灰石修饰前后粒径尺寸由4.149 μm减小到3.595 μm，比表面积由60.6 m2·g-1减小到28.0 m2·g-1.

Abstract:

The hydroxyapatite (HAP) modified by dimer acid was prepared in different solvents under different technology conditions by using C36 dimer acid and porous hydroxyapatite as raw materials. The structure of the modified hydroxyapatites was characterized by Fourier transform infrared spectrum analyzer (FTIR), laser particle analyzer, Bet surface area analyzer (BET) and scanning electron microscope (SEM). The progress of reaction was estimated by thermogravimetric (TG) ananlysis. The results show that the porous hydroxyapatite modified by dimer acids can be obtained at the reaction temperature of 105~110 ℃, the dosage mass ratio of C36 dimer acid to porous hydroxyapatite of 1∶1 and in the solvent of ethanol for 3.5~4.0 h. Under the above reaction conditions, the progress of the reaction was estimated by 36% or so. The dimer acids are on the surface and in the pore structure of hydroxyapatite which results in the decrease of the porosity of HAP. After the modification by dimer acids, the particle size of HAP decreases from 4.149 μm to 3.595 μm. And the BET specific surface area of HAP decreases from 60.6 to 28.0 m2·g-1.