Abstract:This paper builds an asymmetrical evolutionary game model of research and development talents between inflow region and outflow region. Through analyzing the phase diagrams, the evolutionary game system’s stability strategies under different conditions are studied. Consequently, the mechanism of the talents’ agglomeration, replacement, dissipation and stagnation is found. The results show that the talents’ decision on mobility is not only based on cost and income, but also based on intangible benefits from the external effect of talent agglomeration. Therefore, the government can choose the evolutionary path by adjusting talent mobility costs, talent subsidies, social benefits and by controlling the convenience of knowledge spillovers.