Abstract:In this paper, conceptual model’s screening problems are solved via using DNA computing method. Firstly, it introduces skeleton structure to represent conceptual model, which is constructed in combination of head, deflection angle and skeleton curve. And then it proposes the deflection angle and skeleton curve DNA encoding method. Secondly, it designs the DNA computing algorithm process, whose feasibility is verified by the computer simulation. The DNA fragments are divided into 5 categories according to their length using K-means method. Thirdly, the evaluation parameter weights are determined by using information entropy calculating method and the evaluation function of conceptual model is established. Finally, the experimental results show that a reasonable evaluation function can basically describe the structural features of conceptual model and it could help designers find solutions effectively and efficiently. Furthermore, some common components can be extracted by comparing their scores due to the conceptual models, because similar scores of models have a high similarly and thus common components can provide raw materials for further design in the future.