Abstract:This paper investigated the spatial pattern and agglomeration of architectural design industry cluster in Yangpu District by introducing the methods of exploratory spatial data analysis. By analyzing the internal spatial structure of cluster, this paper explored the changes of the innovation agglomeration with the spatial scale and step width, and studied the spatial distribution of the cluster network from the horizontal and vertical dimensions respectively based on the analysis of influencing factors. It is discovered that the spatial distribution of innovation cluster displays an obvious core periphery pattern derived from the joint effects of centripetal force consists of correlation effects, knowledge spillovers and other external economic and centrifugal forces generated by land rent and crowdedness. Moreover, the “core” comprised of the knowledge source with Tongji University as a representative created the localized force through the exchange of knowledge and information and enhancement of institutional model. Based on the “core”, the firms make their spatial decision according to the localized suitability of product, scale and complexity of technology with traffic network structure as a constraint, which constitutes the core mechanism of spatial organization pattern of innovation clusters.