Abstract:A novel registration method for optical and Synthetic Apperture Radar(SAR) satellite images based on artificial immunity algorithm (AIA) was proposed. By taking into account of the sufficient spectral information from optical satellite image, areal features were extracted from optical image based on the image classification strategy. Then the affine transformation with initial transformation parameters was adopted to obtain the new coordinates of features according to the location of features in optical image. Finally, the transformation parameters were optimized based on AIA by using the homogeneity of corresponding areas in SAR image, which were determined by the new coordinates of areal features, as the criterion of the transformation parameters. WorldView 2 and RadarSat 2 images were used to verify the effect of the proposed image registration method for optical and SAR satellite images. It is proved that the RMSE of image registration is less than 2 pixels.