Abstract:Based on two dimensions of organizational type and regional boundary, this paper examines the effect of university cooperation mode on academic innovation performance with the coauthor paper data of Shanghai in 2013. Results show that the cooperation mode has an effect on academic innovation performance; interregional cooperation to enhance academic innovation performance is better than intraregional cooperation, but the mode of universityindustry cooperation across the region has not significant effect on the academic innovation performance. This suggests that the geographical proximity effect is gradually weakening, but the overlap effect of geographical proximity and organizational proximity still has certain blocking effect. In addition, the differences of academic innovation performance in different research areas were also investigated.