用于放射治疗的Dy2O3Li2OB2O3玻璃的性质

Properties of Dy2O3Li2OB2O3 Glass Used as Radiotherapy

摘要:

采用传统熔融法制备了Dy2O3Li2OB2O3(DyLB)玻璃，并对其中7种组成的玻璃性质进行了研究.测定了它们的密度和显微硬度；测试了玻璃在人体模拟液(SBF)中的化学稳定性.实验结果表明：当Li2O质量分数固定为11%，Dy2O3在10%～22%区域内变化时，随Dy2O3含量的增加，DyLB玻璃的密度升高，玻璃的显微硬度先降低后升高，玻璃在SBF溶液中的溶出率降低，并且溶出率随浸泡时间的延长而增加.对其中1个组成的玻璃制备成玻璃微球，用中子反应堆对微球进行了辐射试验.DyLB微球辐照的数据表明，Li和

Abstract:

Dy2O3Li2O-B2O3 (DyLB) glasses were prepared by traditional melting method. Properties of the glasses with seven different compositions were investigated by density and hardness measurements. The chemical durability of these glasses in simulated body fluid (SBF) was also studied. Results show that when the Dy2O3 content ranges from 10 to 22% and the Li2O content is 11%,the density increases and the dissolution rate decreases,but their hardness first decreases and then increases.With the increasing of Dy2O3 content,the dissolution rate of all glasses increases with the prolonging of the immersion time.Glass microspheres were made from one of the seven compositions and were testd by a neutron bombardment reactor. The radiation results for DyLB glass microspheres show that the radiated 8Li and 12B are nuclides with short halflife.Only 165Dy nuclide with halflife of 2.4 h can emit β rays, which can be used in radiotherapy in clinic.