Abstract:University technology transfer is a complex process with four participants (enterprises,intermediary organizations, universities, and the government) and multi-targets. However, previous research normally focused on signal participant or signal stage, rather than from system perspective. In order to narrow this gap, this study attempts to investigate the process of university technology transfer comprehensively to find the most significant impact factors.The questionnaire was designed and set to 204 responses coming from universities, research institutes, enterprises, intermediary organizations, and different government departments in Shanghai. The factor analysis method and structural equation model was adopted. Study results show that both technology supplying and demanding need improving. In order to promote university technology transfer, the reasonable management mode should be employed according to latest incentive policies. In addition, from the public policy perspective, the government should put more emphasis on enterprises’ technological absorptive capacity.